Apricus Biosciences, Inc. today announced that an additional analysis conducted on behalf of the Company has shown that MycoVa?„? has successfully demonstrated ‘non-inferiority’ for the treatment of onychomycosis (commonly referred to as nail fungus), compared to the current standard of care in Europe for topical therapy, Loceryl?®.
The advantage of Apricus Bio’s MycoVa?„? is that it is easy to apply, thus improving patient compliance. MycoVa?„? is applied to the infected nails, typically at bedtime, with minimal preparation, such as simply washing with soap and water. The formulation allows significant amounts of the drug to penetrate through the nail plate to the nail bed and surrounding area where fungus is located. By contrast, Loceryl?® requires more patient care before applying the lacquer. For Loceryl?®, this includes filing the affected areas of nail, including the nail surfaces, as thoroughly as possible. The surface of the nail should then be cleansed using disposable swabs. The nail lacquer should be applied onto the entire surface of the infected nail(s) using reusable applicators. Before repeat application of Loceryl?®, the affected nails should be filed down again as required, following cleansing with a cleaning pad to remove any residual lacquer.
Onychomycosis is a chronic persistent fungal infection of the nail bed resulting in thickening and discoloration of the nail, which sometimes can be accompanied by serious pain and disability. According to the Merck Manual, the worldwide incidence rate of onychomycosis is approximately 10%. As described by Iorizzo and Piraccini (2007), the incidence has been increasing due to diabetes, immunosuppression and an aging population. While occurring in approximately 2.6% of children younger than 18 years, it occurs in as much as 90% of the elderly population (eMedicine.medscape). As of 2008, Thomson Reuters Pharma has stated that the worldwide market is approximately $2.8 billion in size and is expected to grow to approximately $2.9 billion by 2014.
SOURCE Apricus Biosciences, Inc.